Inheritance, variation and evolution
- Reproduction
- Sexual vs asexual, meiosis
- Gametes fuse, variety
- One parent, clones
- Meiosis halves chromosomes
- Fertilisation restores number
- Pros and cons Triple only
- Variation
- Faster, one parent
- Malaria, fungi, plants
- DNA and genome
- Double helix
- Gene codes for protein
- Human genome uses
- DNA structure Triple only
- Nucleotides: sugar, phosphate, base
- Bases A, C, G, T
- Three bases, one amino acid
- Protein synthesis and mutations Triple onlyHigher tier
- C–G, T–A pairing
- Ribosomes, carrier molecules
- Mutation changes protein shape
- Non-coding DNA switches genes
- Genetic inheritance
- Alleles
- Dominant, recessive
- Punnett squares
- Family trees
- Inherited disorders
- Polydactyly
- Cystic fibrosis
- Embryo screening
- Sex determination
- XX female
- XY male
- 1 : 1 ratio
- Sexual vs asexual, meiosis
- Variation and evolution
- Variation
- Genetic
- Environmental
- Both
- Mutations
- Source of variants
- Most no effect
- Rare new phenotype
- Evolution
- Natural selection
- Survive and breed
- New species
- Selective breeding
- Choose parents
- Many generations
- Inbreeding
- Genetic engineering
- Gene from another organism
- GM crops
- Human insulin
- Steps of genetic engineering Higher tier
- Enzymes isolate gene
- Vector: plasmid or virus
- Insert into cells
- Cloning Triple only
- Tissue culture
- Cuttings
- Embryo transplants
- Adult cell cloning
- Variation
- Development of understanding
- Darwin Triple only
- Observations
- Origin of Species 1859
- Gradual acceptance
- Lamarck Triple only
- Inheritance of acquired changes
- Rarely true
- Wallace and speciation Triple only
- Joint writings 1858
- Warning colouration
- Steps to new species
- Mendel and genes Triple only
- Units passed on
- Chromosomes observed
- DNA structure
- Evidence for evolution
- Genes
- Fossils
- Antibiotic resistance
- Fossils
- How formed
- Record incomplete
- Extinction
- New predators, diseases
- New competitors
- Environmental change
- Catastrophic event
- Resistant bacteria
- Mutation
- Survive and reproduce
- MRSA
- Reduce misuse
- Darwin Triple only
- Classification
- Linnaean system
- Kingdom to species
- Carl Linnaeus
- Binomial names
- Genus
- Species
- Three-domain system
- Archaea
- Bacteria
- Eukaryota
- Evolutionary trees
- Classification data
- Fossil data
- Common ancestors
- Linnaean system