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Sex hormones in humans — Cambridge IGCSE Combined Science

The stages of the menstrual cycle and how the lining of the uterus changes over about 28 days.

Spec B14.2Reproduction, subtopic 3 of 3

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  1. The menstrual cycle lasts about 28 days with ovulation around day 14, controlled by FSH, LH, oestrogen and progesterone. Cambridge IGCSE Biology 16.5.

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Quick check questions

  1. What happens to the uterus lining during menstruation?

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    It breaks down and is lost through the vagina with blood.

  2. About how long is one menstrual cycle?

    Show answer

    About 28 days.

  3. What happens to the uterus lining after menstruation?

    Show answer

    It is repaired and thickens, ready for a fertilised egg.

Written and checked against the Cambridge IGCSE Combined Science (0653) specification · Updated October 2026