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Antibiotics and painkillers

Infection and response · Communicable diseases · note 8 of 9

Antibiotics and painkillersSpec 4.3.1.8

In short

Antibiotics, such as penicillin, are medicines that help to cure bacterial disease by killing infective bacteria inside the body. Specific bacteria should be treated with specific antibiotics. Antibiotics cannot kill viruses, and the emergence of strains resistant to antibiotics is of great concern. Painkillers and other medicines treat the symptoms of disease but do not kill pathogens.

Antibiotics, such as penicillin, are medicines that help to cure bacterial disease by killing infective bacteria inside the body.

It is important that specific bacteria are treated by specific antibiotics.

The use of antibiotics has greatly reduced deaths from infectious bacterial diseases. However, the emergence of strains resistant to antibiotics is of great concern.

What antibiotics cannot do

  • Antibiotics cannot kill viral pathogens.
  • It is difficult to develop drugs that kill viruses without also damaging the body's tissues, because viruses live and reproduce inside cells.

Painkillers

Painkillers and other medicines are used to treat the symptoms of disease but do not kill pathogens.

Antibiotics and painkillers compared
AntibioticsPainkillers
What they doKill bacteria inside the bodyTreat symptoms such as pain
Do they kill pathogens?Yes, bacteria onlyNo
Work on viruses?NoThey do not kill them, but can ease symptoms
Exam tip:

If asked why an antibiotic is not given for a viral illness, say that antibiotics cannot kill viruses. Do not say that viruses are 'too small'.

Written and checked against the AQA GCSE Combined Science (8464) specification · Updated October 2026

Frequently asked questions

How do pathogens spread?

Pathogens spread by direct contact, by water or by air. HIV and gonorrhoea spread by sexual contact, and HIV also by the exchange of body fluids such as blood. Measles spreads in droplets from sneezes and coughs, and rose black spot by water or wind. Salmonella spreads in food, and malaria is carried by mosquitos.

How do white blood cells fight infection?

White blood cells fight infection in three ways. Some engulf and digest pathogens, which is called phagocytosis. Others produce antibodies, which target a particular pathogen and help to destroy it, and antitoxins, which neutralise the toxins released by pathogens. This is the immune system, which acts when a pathogen gets past the non-specific defences.

How do vaccines work?

Vaccines work by introducing small quantities of dead or inactive pathogen into the body, which stimulates white blood cells to produce antibodies. If the same pathogen enters the body later, the white blood cells respond quickly to make the correct antibodies, so the pathogen is destroyed before it causes illness. A vaccine does not contain antibodies itself.

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