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Size and scale

Organisation · Principles of organisation · note 2 of 2

Size and scaleSpec 4.2.1

In short

Each level of organisation is bigger than the one before: a tissue is many cells, and an organ is many tissues. Most cells are only tens of micrometres across, so you need a microscope to see them, while tissues and organs are measured in millimetres or centimetres. To compare sizes, convert mm to µm by multiplying by 1000.

Each level of organisation is bigger than the one before. A tissue is many cells, an organ is many tissues, and an organ system is several organs.

Most cells are only tens of micrometres (µm) across, so you need a microscope to see them. Tissues and organs are large enough to see with the naked eye, and are measured in millimetres (mm) or centimetres (cm).

To compare sizes you must use the same unit for both. To change mm to µm, multiply by 1000.

How many cells fit across a tissue?

A strip of tissue is 2 mm wide. Each cell is 40 µm wide. How many cells fit across the strip?

  1. Convert 2 mm to µm: 2 × 1000 = 2000 µm.
  2. Divide the width of the tissue by the width of one cell: 2000 ÷ 40.

Answer: 50 cells

Maths skill:

Always check the units match before you divide. Mixing mm and µm is the most common mistake in size and scale questions.

Quick check

  1. What is a tissue?

    Show answer

    A group of cells with a similar structure and function.

  2. Why is the stomach an organ?

    Show answer

    It is made of several tissues that work together to perform a specific function.

  3. Put these in order from smallest to largest: organ, cell, organ system, tissue.

    Show answer

    Cell, tissue, organ, organ system.

  4. How many micrometres are in 1 mm?

    Show answer

    1000 µm.

Written and checked against the AQA GCSE Combined Science (8464) specification · Updated October 2026

Frequently asked questions

What is the difference between a tissue and an organ?

A tissue is a group of cells with a similar structure and function, such as muscular tissue. An organ is an aggregation of several tissues performing specific functions. The stomach is an organ because muscular, glandular and epithelial tissues work together in it: one churns the food, one makes digestive juices and one covers its surfaces.

What are the levels of organisation in biology?

The levels of organisation, from smallest to largest, are cells, tissues, organs, organ systems and the whole organism. Each level is made from the one below it. For example, muscle cells form muscular tissue, which is part of the stomach, an organ in the digestive system. In a plant, a palisade cell is part of a leaf.

What is an organ system?

An organ system is a group of organs that work together, and organ systems work together to form organisms. The digestive system is an example: organs such as the stomach, pancreas and small intestine work together to digest and absorb food. In plants, the roots, stem and leaves form an organ system for transport.

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