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Agriculture and evaluating biotechnology — Edexcel GCSE Combined Science

How to evaluate the benefits and risks of genetic engineering and selective breeding in agriculture and medicine, including ethical issues.

Spec 4.13B–4.14Natural selection and genetic modification, subtopic 5 of 5

Revision notes

1 short note, in the order of the specification. Each one in short:

  1. Evaluating genetic engineering and selective breeding means weighing up their benefits and risks, including practical and ethical implications, then reaching a judgement. Selective breeding raises yields but takes many generations and reduces genetic variation. Genetic engineering is quicker and can produce medicines such as human insulin, but it has unknown effects and raises ethical concerns.

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Exam questions

2 exam-style questions (8 marks), each with its mark scheme.

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Flashcards

5 cards: flip them, mark what you knew, and practise the rest.

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Mind map

The whole of natural selection and genetic modification on one page, so you can see where this subtopic fits.

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Quick check questions

  1. What does 'evaluate' require you to do in a question about genetic engineering?

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    Weigh up benefits and risks, including practical and ethical implications, and reach a judgement.

  2. Name one practical and one ethical implication of genetic engineering.

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    Practical: it is costly or may not work. Ethical: some think it is wrong to alter the genes of organisms.

  3. Give one risk of selective breeding.

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    It reduces genetic variation, or inbreeding causes health problems.

Frequently asked questions

What are the ethical issues with genetic engineering?

The ethical issues with genetic engineering are about what people think is right or wrong. Some people think it is wrong or unnatural to change the genes of living things, especially animals, and there are concerns about animal welfare. Alongside these, there are risks such as unknown effects on the environment and human health.

Is genetic engineering better than selective breeding?

Neither is better in every case, so you must weigh them up. Genetic engineering is quicker and can add new characteristics, such as insect resistance, or make medicines like human insulin, but it may have unknown effects. Selective breeding needs no special equipment but takes many generations, reduces genetic variation and can cause inbreeding problems.

Written and checked against the Edexcel GCSE Combined Science (1SC0) specification · Updated October 2026