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Evaluating genetic engineering and selective breeding

Natural selection and genetic modification · Agriculture and evaluating biotechnology · note 1 of 1

Evaluating genetic engineering and selective breedingSpec 4.14

In short

Evaluating genetic engineering and selective breeding means weighing up their benefits and risks, including practical and ethical implications, then reaching a judgement. Selective breeding raises yields but takes many generations and reduces genetic variation. Genetic engineering is quicker and can produce medicines such as human insulin, but it has unknown effects and raises ethical concerns.

'Evaluate' means weigh up benefits and risks, including practical and ethical implications, and reach a judgement. Here are the main points for agriculture and medicine.

Benefits and risks
BenefitsRisks and implications
Selective breedingHigher yields and better quality food; no special equipment needed; produces useful animals and plantsTakes many generations; reduces genetic variation; inbreeding can cause health problems in animals
Genetic engineering in agricultureCrops with new characteristics such as insect resistance or greater nutritional value; quicker than selective breedingUnknown effects on the environment and human health; genes may spread to wild species; some people think it is wrong to alter genes
Genetic engineering in medicineMedicines such as human insulin can be made in large amounts from GM organismsPossible unforeseen effects; ethical concerns about changing the genes of organisms, especially animals

Practical implications include time, cost, skill and the chance that it does not work. Ethical implications are about what people think is right or wrong, such as animal welfare and whether humans should change the genes of living things.

Interpreting yield data (practice data)

A farmer grows a non-GM crop with a yield of 4.0 tonnes per hectare, and a GM crop with a yield of 5.0 tonnes per hectare. Calculate the percentage increase in yield with the GM crop.

  1. Increase = 5.0 − 4.0 = 1.0 tonnes per hectare
  2. Percentage increase = increase ÷ original × 100
  3. 1.0 ÷ 4.0 × 100 = 25%

Answer: 25% increase.

Maths skill:

When asked to plot or read data from graphs or tables, check the axis scales and units, and use values from the data in your evaluation.

Exam tip:

In a 6-mark 'evaluate' answer, give benefits and risks, include both practical and ethical points, and finish with a clear conclusion that uses them.

Quick check

  1. What does 'evaluate' require you to do in a question about genetic engineering?

    Show answer

    Weigh up benefits and risks, including practical and ethical implications, and reach a judgement.

  2. Name one practical and one ethical implication of genetic engineering.

    Show answer

    Practical: it is costly or may not work. Ethical: some think it is wrong to alter the genes of organisms.

  3. Give one risk of selective breeding.

    Show answer

    It reduces genetic variation, or inbreeding causes health problems.

Written and checked against the Edexcel GCSE Combined Science (1SC0) specification · Updated October 2026

Frequently asked questions

What are the ethical issues with genetic engineering?

The ethical issues with genetic engineering are about what people think is right or wrong. Some people think it is wrong or unnatural to change the genes of living things, especially animals, and there are concerns about animal welfare. Alongside these, there are risks such as unknown effects on the environment and human health.

Is genetic engineering better than selective breeding?

Neither is better in every case, so you must weigh them up. Genetic engineering is quicker and can add new characteristics, such as insect resistance, or make medicines like human insulin, but it may have unknown effects. Selective breeding needs no special equipment but takes many generations, reduces genetic variation and can cause inbreeding problems.

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