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The need to transport substances

Exchange and transport in animals · Transport and exchange surfaces · note 1 of 3

The need to transport substancesSpec 8.1

In short

Substances must be transported into and out of an organism and its cells. Oxygen, dissolved food molecules, water and mineral ions are needed by cells, while carbon dioxide from respiration and urea are waste products that must be removed. In a large animal many cells are far from the outside, so blood transports these substances.

Every cell in an organism needs a supply of some substances and must get rid of others. These substances have to be transported into and out of the organism and its cells.

Substances that are transported and why
SubstanceDirectionWhy it is needed
OxygenInto cellsUsed in aerobic respiration to release energy
Carbon dioxideOut of cellsWaste product of respiration. It must be removed from the body
WaterInto and out of cellsNeeded for cell reactions and to keep cells working. Water is also lost from the body, for example in urine and sweat
Dissolved food moleculesInto cellsProvide a source of energy and the materials for growth and repair, for example glucose and amino acids
Mineral ionsInto cellsNeeded for many cell processes
UreaOut of cellsA waste product that is made in the body. It is carried in the blood to the kidneys and removed in urine

In a single-celled organism these substances can simply diffuse across the cell surface. In a large animal many cells are far from the outside world, so substances have to be moved over long distances. Blood is the transport medium in humans.

Exam tip:

When asked to describe the need for transport, name the substance, say whether it goes in or out, and give the reason. For example: carbon dioxide is a waste product of respiration, so it must be removed.

Written and checked against the Edexcel GCSE Combined Science (1SC0) specification · Updated October 2026

Frequently asked questions

How are alveoli adapted for gas exchange?

Alveoli are adapted for gas exchange by having a very large surface area, from millions of alveoli, and walls only one cell thick for a short diffusion distance. A rich network of capillaries and ventilation keep a steep concentration gradient, and a moist lining lets gases dissolve, which helps them to diffuse.

Why is the surface area to volume ratio important for cells?

The surface area to volume ratio matters because substances enter and leave across the surface. A single-celled organism has a large ratio and a short diffusion distance, so diffusion is fast enough. A large multicellular organism has a small ratio and many cells deep inside the body, so diffusion across its body surface alone would be far too slow.

How do you calculate surface area to volume ratio?

To calculate the surface area to volume ratio, divide the surface area by the volume and write the answer in the form x : 1. For a cube with 3 cm sides, the surface area is 6 × 9 = 54 cm² and the volume is 27 cm³, so the ratio is 54 ÷ 27 = 2 : 1.

All 4 questions on Transport and exchange surfaces