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Metabolism

Bioenergetics · Respiration · note 3 of 3

MetabolismSpec 4.4.2.3

In short

Metabolism is the sum of all the reactions in a cell or the body. It uses energy transferred by respiration for enzyme controlled processes that make new molecules. It includes converting glucose to starch, glycogen and cellulose, forming lipids from one glycerol and three fatty acids, making amino acids and proteins, respiration, and breaking down excess proteins to form urea.

Metabolism is the sum of all the reactions in a cell or the body.

The energy transferred by respiration in cells is used by the organism for the continual enzyme controlled processes of metabolism that synthesise new molecules.

Metabolism includes:

  • conversion of glucose to starch, glycogen and cellulose
  • the formation of lipid molecules from a molecule of glycerol and three molecules of fatty acids
  • the use of glucose and nitrate ions to form amino acids, which in turn are used to synthesise proteins
  • respiration
  • breakdown of excess proteins to form urea for excretion.
Synthesis and breakdown of large molecules
Large moleculeMade from (synthesis)Broken down into (breakdown)
Carbohydrates (starch, glycogen, cellulose)Sugars such as glucoseSugars
ProteinsAmino acidsAmino acids
LipidsOne glycerol and three fatty acidsFatty acids and glycerol

So sugars, amino acids, fatty acids and glycerol are the building blocks used to make carbohydrates, proteins and lipids, and the molecules that those large molecules are broken down into.

Exam tip:

A lipid is made from one glycerol and three fatty acids. Learn the numbers 1 and 3.

All of these aspects are covered in more detail in the relevant specification sections but are linked together here.

Hub diagram with Metabolism in the centre and arrows to: respiration; glucose to starch, glycogen and cellulose; 1 glycerol + 3 fatty acids to lipid; glucose + nitrate ions to amino acids to proteins; excess proteins to urea for excretion. (opens full size in a new tab)
Metabolism is the sum of all the reactions in a cell or the body.

Quick check

  1. Write the word equation for aerobic respiration.

    Show answer

    glucose + oxygen → carbon dioxide + water

  2. What are the products of anaerobic respiration in yeast?

    Show answer

    Ethanol and carbon dioxide.

  3. Why does anaerobic respiration transfer much less energy than aerobic respiration?

    Show answer

    Because the oxidation of glucose is incomplete.

  4. Name the three things that increase during exercise to supply muscles with more oxygenated blood.

    Show answer

    Heart rate, breathing rate and breath volume.

  5. What is metabolism?

    Show answer

    The sum of all the reactions in a cell or the body.

Written and checked against the AQA GCSE Biology (8461) specification · Updated October 2026

Frequently asked questions

Why is respiration an exothermic reaction?

Respiration is exothermic because energy is transferred from the reaction to the surroundings. It happens continuously in living cells, and the energy transferred supplies all the energy needed for living processes, such as chemical reactions to build larger molecules, movement and keeping warm. Both aerobic and anaerobic respiration transfer energy in this way.

How is respiration different from breathing?

Respiration is a chemical reaction that happens inside living cells to transfer energy from glucose. Breathing moves air into and out of the lungs, which supplies the oxygen used in aerobic respiration. Respiration happens all the time in every living cell, including plant cells, not only at night, and it can also happen anaerobically without oxygen.

What is anaerobic respiration in yeast?

Anaerobic respiration in yeast is respiration without oxygen, in which glucose is converted into ethanol and carbon dioxide. It is called fermentation, and it has economic importance in the manufacture of bread and alcoholic drinks. Much less energy is transferred than in aerobic respiration, because the oxidation of glucose is incomplete.

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