Book a tutor

The heart and the double circulatory system

Organisation · Animal tissues, organs and organ systems · note 7 of 20

The heart and the double circulatory systemSpec 4.2.2.2

In short

The heart is an organ that pumps blood around a double circulatory system, so blood passes through it twice on each complete circuit. The right ventricle pumps blood to the lungs for gas exchange, and the left ventricle pumps blood around the rest of the body. The left ventricle has a thicker wall, and valves stop blood flowing backwards.

The heart is an organ that pumps blood around the body in a double circulatory system. There are two separate loops, and blood passes through the heart twice on each complete circuit.

  • The right ventricle pumps blood to the lungs, where gas exchange takes place.
  • The left ventricle pumps blood around the rest of the body.

Blood returns from the body to the right atrium and from the lungs to the left atrium. The ventricles have thick muscular walls. The left ventricle has a thicker wall than the right, because it has to pump blood all the way around the body at a higher pressure. Valves in the heart stop blood flowing backwards. You do not need to know the names of the valves.

Blood vessels associated with the heart
VesselCarries bloodOxygen content
Vena cavaFrom the body to the right atriumLow (deoxygenated)
Pulmonary arteryFrom the right ventricle to the lungsLow (deoxygenated)
Pulmonary veinFrom the lungs to the left atriumHigh (oxygenated)
AortaFrom the left ventricle to the bodyHigh (oxygenated)
Coronary arteriesOver the surface of the heart, supplying the heart muscleHigh (oxygenated)
  1. Deoxygenated blood from the body enters the right atrium through the vena cava.
  2. It passes into the right ventricle, which pumps it to the lungs through the pulmonary artery.
  3. In the lungs the blood picks up oxygen and loses carbon dioxide.
  4. Oxygenated blood returns through the pulmonary vein to the left atrium.
  5. It passes into the left ventricle, which pumps it around the body through the aorta.
A section through the heart showing the right atrium, right ventricle, left atrium, left ventricle, valves, vena cava, pulmonary artery, pulmonary vein, aorta and coronary arteries, with blue arrows for deoxygenated blood and red arrows for oxygenated blood. (opens full size in a new tab)
Blue arrows: deoxygenated blood to the lungs. Red arrows: oxygenated blood to the body. The left ventricle has the thickest wall.
Common mistake:

The pulmonary artery carries deoxygenated blood and the pulmonary vein carries oxygenated blood. This is the opposite of most arteries and veins. Remember: arteries carry blood away from the heart.

Exam tip:

On a heart diagram, left and right are the patient's left and right. The patient's left side appears on the right of the page.

Written and checked against the AQA GCSE Biology (8461) specification · Updated October 2026

Frequently asked questions

Why do enzymes denature at high temperatures?

At high temperatures the shape of the enzyme's active site changes, so the substrate no longer fits and the reaction cannot be catalysed. The enzyme is denatured, and this cannot be changed back. Below the optimum, the rate rises with temperature because particles move faster and collide more often. Enzymes are not killed, because they are not alive.

How are alveoli adapted for gas exchange?

Millions of alveoli give a very large surface area for diffusion. Their walls are one cell thick, so the diffusion distance is short. A network of capillaries carries oxygen away and brings carbon dioxide, and constant ventilation brings fresh air. Both keep a steep concentration gradient, so oxygen diffuses into the blood and carbon dioxide diffuses out quickly.

Why is the left ventricle thicker than the right?

The left ventricle has a thicker muscular wall than the right because it pumps blood all the way around the body at a higher pressure. The right ventricle only pumps blood to the lungs. Both are part of the double circulatory system, in which blood passes through the heart twice on each complete circuit.

All 5 questions on Animal tissues, organs and organ systems