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The use of hormones to treat infertility

Homeostasis and response · Hormonal coordination in humans · note 10 of 11

Spec 4.5.3.6
Higher tier (what this means)Higher tier: only on the Higher tier papers. Foundation students can skip it. What the labels mean
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The use of hormones to treat infertilitySpec 4.5.3.6

In short

Infertility can be treated with a fertility drug containing FSH and LH, so a woman may then become pregnant normally. In IVF, FSH and LH make several eggs mature. The eggs are collected and fertilised by sperm in the laboratory, and one or two embryos are inserted into the uterus. IVF is stressful and success rates are not high.

Hormones are used in modern reproductive technologies to treat infertility. A ‘fertility drug’ contains FSH and LH given to a woman. She may then become pregnant in the normal way.

In vitro fertilisation (IVF)

  1. The mother is given FSH and LH to stimulate the maturation of several eggs.
  2. The eggs are collected from the mother and fertilised by sperm from the father in the laboratory.
  3. The fertilised eggs develop into embryos.
  4. At the stage when they are tiny balls of cells, one or two embryos are inserted into the mother’s uterus (womb).

Evaluating fertility treatment

Fertility treatment gives a woman the chance to have a baby of her own. However:

  • it is very emotionally and physically stressful
  • the success rates are not high
  • it can lead to multiple births, which are a risk to both the babies and the mother.
Exam tip:

Give a balanced answer for IVF: the benefit is a baby of her own; the problems are stress, low success rates and the risks of multiple births. Social and ethical views also matter.

Written and checked against the AQA GCSE Biology (8461) specification · Updated October 2026

Frequently asked questions

What does insulin do to blood sugar?

Insulin lowers blood sugar (blood glucose concentration). The pancreas produces insulin when blood glucose is too high, for example after a meal. Insulin causes glucose to move from the blood into the cells, and in liver and muscle cells excess glucose is converted to glycogen for storage. Blood glucose then falls back to the normal level.

What is the difference between insulin and glucagon?

Higher tier Insulin lowers blood glucose and glucagon raises it. Both are made by the pancreas. Insulin is released when blood glucose is too high and makes glucose move from the blood into cells. Glucagon is released when it is too low and causes glycogen to be converted into glucose and released into the blood. They work in a negative feedback cycle.

Why are hormones called chemical messengers?

Hormones are called chemical messengers because they are chemicals secreted by glands directly into the bloodstream, which carries them to a target organ where they produce an effect. Compared with nerve impulses, hormones act more slowly but their effects last longer. They reach every part of the body but only affect their target organ.

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