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Communicable (infectious) diseases

Infection and response · Communicable diseases · note 1 of 9

Communicable (infectious) diseasesSpec 4.3.1.1

In short

A pathogen is a microorganism that causes infectious disease, and may be a virus, bacterium, protist or fungus. Communicable diseases are spread by direct contact, by water or by air. Bacteria and viruses may reproduce rapidly inside the body. Bacteria may produce toxins that damage tissues, and viruses live and reproduce inside cells, causing cell damage.

Pathogens are microorganisms that cause infectious disease. Pathogens may be viruses, bacteria, protists or fungi. They may infect plants or animals.

Pathogens depend on their host to provide the conditions and nutrients they need to grow and reproduce.

How pathogens spread

Pathogens can be spread by direct contact, by water or by air.

Routes of infection, with examples from this topic
RouteExamples
Direct contactHIV (sexual contact, exchange of body fluids such as blood); gonorrhoea (sexual contact)
WaterRose black spot in plants (spread in the environment by water)
AirMeasles (inhaling droplets from sneezes and coughs); rose black spot (spread by wind)
Other routes in the specSalmonella (in food, or on food prepared in unhygienic conditions); malaria (carried by mosquitos)

How pathogens make us ill

  • Bacteria and viruses may reproduce rapidly inside the body.
  • Bacteria may produce poisons called toxins that damage tissues and make us feel ill.
  • Viruses live and reproduce inside cells, causing cell damage.

Reducing or preventing the spread

To explain how spread can be reduced, link the method to the way the disease is passed on.

  • Good hygiene, such as washing hands and preparing food hygienically, reduces spread by contact and in food.
  • Covering the mouth and nose when coughing or sneezing, and keeping infected people away from others, reduces spread through the air.
  • Vaccination prevents people from becoming infected.
  • Controlling vectors, such as stopping mosquitos from breeding, and avoiding bites reduces the spread of malaria.
  • Barrier contraception (a condom) and not sharing needles reduce the spread of sexually transmitted and blood-borne diseases.
  • Treating infected people, for example with antibiotics for gonorrhoea, reduces the chance of them passing the pathogen on.
  • In plants, destroying infected leaves and using fungicides reduce the spread of fungal disease.
Exam tip:

For a 'how can the spread be reduced' question, name the method and say why it works. 'Wash hands' alone is not enough; add 'to remove pathogens that could be passed on by contact'.

Pathogen
A microorganism that causes infectious disease.
Toxin
A poison produced by bacteria that damages tissues and makes us feel ill.

Written and checked against the AQA GCSE Biology (8461) specification · Updated October 2026

Frequently asked questions

How do pathogens spread?

Pathogens spread by direct contact, by water or by air. HIV and gonorrhoea spread by sexual contact, and HIV also by the exchange of body fluids such as blood. Measles spreads in droplets from sneezes and coughs, and rose black spot by water or wind. Salmonella spreads in food, and malaria is carried by mosquitos.

How do white blood cells fight infection?

White blood cells fight infection in three ways. Some engulf and digest pathogens, which is called phagocytosis. Others produce antibodies, which target a particular pathogen and help to destroy it, and antitoxins, which neutralise the toxins released by pathogens. This is the immune system, which acts when a pathogen gets past the non-specific defences.

How do vaccines work?

Vaccines work by introducing small quantities of dead or inactive pathogen into the body, which stimulates white blood cells to produce antibodies. If the same pathogen enters the body later, the white blood cells respond quickly to make the correct antibodies, so the pathogen is destroyed before it causes illness. A vaccine does not contain antibodies itself.

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