Homeostasis and temperature control — Edexcel GCSE Biology
Why the body keeps its internal environment constant, and how the skin and brain control body temperature.
Why the body keeps its internal environment constant, and how the skin and brain control body temperature.
4 short notes, in the order of the specification. Each one in short:
Homeostasis is maintaining a constant internal environment in response to internal and external change. The body keeps blood glucose concentration, body temperature and the water content of the blood within narrow limits. This matters because enzymes and cells work best in a narrow range of conditions. Many of these controls use negative feedback.
Thermoregulation is the control of body temperature at about 37°C, the optimum for most enzymes: too hot and enzymes are denatured, too cold and reactions are too slow. Osmoregulation is the control of the water content of the blood. If the blood is too dilute, water enters animal cells by osmosis and they swell; too concentrated, and they shrink.
The hypothalamus in the brain is the control centre for body temperature. It monitors the temperature of the blood and receives impulses from temperature receptors in the dermis of the skin. It then sends nerve impulses to effectors such as the sweat glands, muscles and blood vessels. Sweat reaches the skin surface through pores in the epidermis.
When the body is too hot, sweat glands release sweat, which evaporates and takes heat from the skin. In vasodilation, the blood vessels supplying the skin widen, so more heat is lost. When the body is too cold, shivering muscles contract rapidly and respiration transfers energy as heat, sweating is reduced, and vasoconstriction narrows the vessels to reduce heat loss.
5 exam-style questions (16 marks), each with its mark scheme.
Answer the questions14 cards: flip them, mark what you knew, and practise the rest.
Practise the cardsThe whole of animal coordination, control and homeostasis on one page, so you can see where this subtopic fits.
Open the mind mapFree PDFs to print or save.
Define homeostasis.
Maintaining a constant internal environment in response to internal and external change.
Why does a high body temperature stop reactions in cells? (Triple only)
Enzymes are denatured, so substrates no longer fit the active site.
What happens to animal cells if the blood is too dilute? (Triple only)
Water enters by osmosis. The cells swell and may burst.
Which part of the brain coordinates temperature control? (Triple only)
The hypothalamus.
How does shivering warm the body? (Triple only)
Muscles contract rapidly. Respiration in the muscle cells transfers energy as heat.
Homeostasis is important because enzymes and cells work best in a narrow range of conditions. If blood glucose concentration, body temperature or the water content of the blood drift too far, reactions in cells slow down or stop. The body responds to changes and brings each condition back to a set level, often using negative feedback.
Triple only Body temperature is regulated by the hypothalamus in the brain, which monitors the temperature of the blood and receives impulses from temperature receptors in the skin. When the body is too hot, sweat glands release sweat, which evaporates and cools the skin. When it is too cold, muscles shiver, and the extra respiration transfers energy as heat.
Triple onlyHigher tier Vasodilation is the widening of the blood vessels supplying the skin surface when the body is too hot, so more blood flows near the surface and more heat is lost. Vasoconstriction is the narrowing of these vessels when the body is too cold, so less blood flows near the surface and less heat is lost.
Triple only At high temperatures enzymes are denatured because the shape of the active site changes, so the substrate no longer fits and the reaction stops. This is why core body temperature is kept at about 37°C, the optimum temperature for most enzymes in the body. Enzymes are proteins, so they are denatured, not killed.
Written and checked against the Edexcel GCSE Biology (1BI0) specification · Updated October 2026