Book a tutor

Fick’s law

Exchange and transport in animals · Factors affecting the rate of diffusion · note 2 of 2

Spec 8.5B
Triple only (what this means)Triple only: only in Triple Biology. Combined Science students can skip it. What the labels mean
Download all Factors affecting the rate of diffusion notes (PDF)Download all notes (PDF)3 pages

Fick’s lawSpec 8.5B

In short

Fick’s law states that the rate of diffusion is proportional to the surface area multiplied by the concentration difference, divided by the thickness of the membrane. Doubling the surface area or the concentration difference doubles the rate, while doubling the membrane thickness halves it. The answer is a relative rate, often given in arbitrary units.

Fick’s law combines the three factors. The rate of diffusion is proportional to the surface area multiplied by the concentration difference, divided by the thickness of the membrane.

rate of diffusion ∝ (surface area × concentration difference) ÷ thickness of membrane

The symbol ∝ means is proportional to. So doubling the surface area doubles the rate, doubling the concentration difference doubles the rate, and doubling the thickness halves the rate.

Using Fick’s law

A membrane has a surface area of 30 units and a thickness of 2 units. The concentration difference across it is 5 units. Calculate the rate of diffusion in arbitrary units.

  1. Multiply surface area by concentration difference: 30 × 5 = 150.
  2. Divide by thickness: 150 ÷ 2 = 75.

Answer: 75 arbitrary units

Maths skill:

Because the law uses proportionality, the answer is a relative rate and is often given in arbitrary units. Show each step of your working to get method marks.

Quick check

  1. Name the three factors that affect the rate of diffusion.

    Show answer

    Surface area, concentration gradient and diffusion distance.

  2. What happens to the rate of diffusion if the membrane becomes twice as thick?

    Show answer

    It halves, if the other factors stay the same.

  3. Write Fick’s law in words.

    Show answer

    Rate of diffusion is proportional to surface area × concentration difference ÷ thickness of membrane.

Written and checked against the Edexcel GCSE Biology (1BI0) specification · Updated October 2026

Frequently asked questions

What affects the rate of diffusion?

The rate of diffusion is affected by surface area, concentration gradient and diffusion distance. A larger surface area lets more particles cross at once, a steeper concentration gradient gives faster net movement, and a shorter distance, meaning a thinner membrane, speeds it up. In the lungs, millions of thin-walled alveoli make diffusion fast.

How does the concentration gradient affect diffusion?

A steeper concentration gradient makes diffusion faster. Diffusion is the net movement of particles from a region of higher concentration to a region of lower concentration, so the bigger the difference, the faster the net movement. In the lungs, blood flow and breathing keep the oxygen concentration lower in the blood than in the alveoli.

What is Fick’s law?

Fick’s law states that the rate of diffusion is proportional to the surface area multiplied by the concentration difference, divided by the thickness of the membrane. Doubling the surface area or the concentration difference doubles the rate, and doubling the thickness halves it. Answers are usually relative rates in arbitrary units, so show each step of working.

Finished factors affecting the rate of diffusion? Test yourself:Exam questionsFlashcards