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The heart and circulatory system

Exchange and transport in animals · The heart and circulation · note 1 of 2

The heart and circulatory systemSpec 8.8

In short

Humans have a double circulatory system: blood goes from the heart to the lungs and back, then from the heart around the body and back. The right ventricle pumps deoxygenated blood to the lungs through the pulmonary artery, and the left ventricle pumps oxygenated blood to the body through the aorta. Valves prevent backflow.

Humans have a double circulatory system. In one circuit the blood goes from the heart to the lungs and back. In the other the blood goes from the heart around the body and back. Blood passes through the heart twice on each complete circuit of the body.

  1. Deoxygenated blood from the body enters the right atrium through the vena cava.
  2. The right atrium contracts and pushes blood into the right ventricle.
  3. The right ventricle contracts and pumps blood to the lungs through the pulmonary artery.
  4. Oxygenated blood returns from the lungs through the pulmonary vein into the left atrium.
  5. The left atrium contracts and pushes blood into the left ventricle.
  6. The left ventricle contracts and pumps blood around the body through the aorta.
Major blood vessels of the heart
Blood vesselCarries bloodBetween
Vena cavaDeoxygenatedBody → right atrium
Pulmonary arteryDeoxygenatedRight ventricle → lungs
Pulmonary veinOxygenatedLungs → left atrium
AortaOxygenatedLeft ventricle → body

Valves

The heart has valves between the atria and ventricles, and where the pulmonary artery and aorta leave the ventricles. They open to let blood through in one direction and close to prevent backflow.

Thickness of the chamber walls

  • The ventricles have thicker, more muscular walls than the atria, because they pump blood out of the heart and further.
  • The left ventricle has a thicker wall than the right ventricle. It pumps blood around the whole body, which needs a higher pressure. The right ventricle pumps blood only to the lungs, which are close by.

The blood pressure falls as blood passes through the capillaries in the lungs. Returning the blood to the heart before it goes to the body lets the left ventricle increase the pressure again, so blood can reach the rest of the body quickly.

Common mistake:

The diagram of the heart is drawn as if you are facing the person, so the left side of the heart is on the right of the page. Check which side is which before you answer.

Diagram of the heart drawn as if facing the person, showing the right atrium and right ventricle on the left of the page and the left atrium and left ventricle on the right, the vena cava, pulmonary artery, pulmonary vein and aorta, valves between the atria and ventricles and at the bases of the pulmonary artery and aorta, the thick muscular wall of the left ventricle, and arrows showing deoxygenated blood in blue and oxygenated blood in red. (opens full size in a new tab)
Blood flows vena cava → right atrium → right ventricle → pulmonary artery, then pulmonary vein → left atrium → left ventricle → aorta. The left side of the heart is on the right of the page.

Written and checked against the Edexcel GCSE Biology (1BI0) specification · Updated October 2026

Frequently asked questions

How does the heart pump blood?

Deoxygenated blood enters the right atrium through the vena cava. The right atrium contracts, pushing blood into the right ventricle, which pumps it to the lungs through the pulmonary artery. Oxygenated blood returns through the pulmonary vein to the left atrium, then the left ventricle pumps it around the body through the aorta. Valves prevent backflow.

Why is the left ventricle thicker than the right?

The left ventricle has a thicker, more muscular wall because it pumps blood around the whole body, which needs a higher pressure. The right ventricle pumps blood only to the lungs, which are close by. The higher pressure matters because blood pressure falls as blood passes through the capillaries in the lungs.

What blood vessels carry blood away from the heart?

Arteries carry blood away from the heart. The aorta carries oxygenated blood from the left ventricle to the body, and the pulmonary artery carries deoxygenated blood from the right ventricle to the lungs. So not all arteries carry oxygenated blood: the pulmonary artery is the exception. Veins carry blood towards the heart.

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