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Units: milli, micro, nano and pico

Key concepts in biology · Microscopy and measuring cells · note 3 of 4

Units: milli, micro, nano and picoSpec 1.5

In short

Milli, micro, nano and pico are units each 1000 times smaller than the one before: 1 mm = 1000 µm, 1 µm = 1000 nm and 1 nm = 1000 pm. To convert to a smaller unit multiply by 1000, and to a larger unit divide by 1000. Standard form uses negative powers of ten for small numbers.

Cells are far too small to measure in metres, so we use smaller units. Each unit below is 1000 times smaller than the one before it.

Units used for cells
PrefixSymbolPower of tenUnit of length
millim10⁻³millimetre (mm)
microµ10⁻⁶micrometre (µm)
nanon10⁻⁹nanometre (nm)
picop10⁻¹²picometre (pm)

To go to a smaller unit, multiply by 1000: mm to µm, µm to nm, nm to pm. To go to a larger unit, divide by 1000. So 1 mm = 1000 µm, 1 µm = 1000 nm and 1 nm = 1000 pm.

Higher tier (what this means)Higher tier: only on the Higher tier papers. Foundation students can skip it. What the labels mean

Standard form

Higher tier (what this means)Higher tier: only on the Higher tier papers. Foundation students can skip it. What the labels mean

Standard form writes a number as a number between 1 and 10 multiplied by a power of ten. For example, 0.000 045 m is 4.5 × 10⁻⁵ m, and 3 200 000 is 3.2 × 10⁶. A negative power means a small number. You must be able to do calculations with numbers written in standard form.

Higher tier (what this means)Higher tier: only on the Higher tier papers. Foundation students can skip it. What the labels mean

Calculating with standard form

A cell is 2.5 × 10⁻⁵ m long. It is viewed at a magnification of ×400. Calculate the length of the image in mm.

  1. image size = real size × magnification
  2. 2.5 × 10⁻⁵ × 400 = 1.0 × 10⁻² m
  3. 1.0 × 10⁻² m = 0.01 m
  4. 0.01 m × 1000 = 10 mm

Answer: 10 mm

Maths skill:

Convert to one unit before you calculate. Mixing mm and µm in one calculation is the most common way to lose marks.

Written and checked against the Edexcel GCSE Biology (1BI0) specification · Updated October 2026

Frequently asked questions

How do you calculate magnification in biology?

Magnification is calculated using magnification = size of image ÷ size of real object. Both sizes must be in the same unit, so convert first, for example from mm to µm by multiplying by 1000. To find the real size, rearrange to real size = image size ÷ magnification. Total microscope magnification is eyepiece × objective.

What is the difference between magnification and resolution?

Magnification is how many times bigger the image is than the real object, while resolution is how well a microscope can show two points close together as separate points. Electron microscopes have a much higher magnification and resolution than light microscopes, so they show fine detail such as ribosomes and the inside of mitochondria.

How many micrometres are in a millimetre?

There are 1000 micrometres (µm) in 1 millimetre. Each unit in the sequence millimetre, micrometre, nanometre and picometre is 1000 times smaller than the one before. To convert to a smaller unit, multiply by 1000; to convert to a larger unit, divide by 1000. For example, 0.2 mm is 200 µm.

All 4 questions on Microscopy and measuring cells