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Evaluating genetic engineering and selective breeding

Natural selection and genetic modification · Agriculture and evaluating biotechnology · note 2 of 2

Evaluating genetic engineering and selective breedingSpec 4.14

In short

Evaluating genetic engineering and selective breeding means weighing up their benefits and risks, including practical and ethical implications, then reaching a judgement. Selective breeding raises yields but takes many generations and reduces genetic variation. Genetic engineering is quicker and can produce medicines such as human insulin, but it has unknown effects and raises ethical concerns.

'Evaluate' means weigh up benefits and risks, including practical and ethical implications, and reach a judgement. Here are the main points for agriculture and medicine.

Benefits and risks
BenefitsRisks and implications
Selective breedingHigher yields and better quality food; no special equipment needed; produces useful animals and plantsTakes many generations; reduces genetic variation; inbreeding can cause health problems in animals
Genetic engineering in agricultureCrops with new characteristics such as insect resistance or greater nutritional value; quicker than selective breedingUnknown effects on the environment and human health; genes may spread to wild species; some people think it is wrong to alter genes
Genetic engineering in medicineMedicines such as human insulin can be made in large amounts from GM organismsPossible unforeseen effects; ethical concerns about changing the genes of organisms, especially animals

Practical implications include time, cost, skill and the chance that it does not work. Ethical implications are about what people think is right or wrong, such as animal welfare and whether humans should change the genes of living things.

Interpreting yield data (practice data)

A farmer grows a non-GM crop with a yield of 4.0 tonnes per hectare, and a GM crop with a yield of 5.0 tonnes per hectare. Calculate the percentage increase in yield with the GM crop.

  1. Increase = 5.0 − 4.0 = 1.0 tonnes per hectare
  2. Percentage increase = increase ÷ original × 100
  3. 1.0 ÷ 4.0 × 100 = 25%

Answer: 25% increase.

Maths skill:

When asked to plot or read data from graphs or tables, check the axis scales and units, and use values from the data in your evaluation.

Exam tip:

In a 6-mark 'evaluate' answer, give benefits and risks, include both practical and ethical points, and finish with a clear conclusion that uses them.

Quick check

  1. What does 'evaluate' require you to do in a question about genetic engineering?

    Show answer

    Weigh up benefits and risks, including practical and ethical implications, and reach a judgement.

  2. Name one practical and one ethical implication of genetic engineering.

    Show answer

    Practical: it is costly or may not work. Ethical: some think it is wrong to alter the genes of organisms.

  3. Give one risk of selective breeding.

    Show answer

    It reduces genetic variation, or inbreeding causes health problems.

Written and checked against the Edexcel GCSE Biology (1BI0) specification · Updated October 2026

Frequently asked questions

What are the advantages and disadvantages of biological control?

Triple only Biological control uses living organisms, such as ladybirds that eat aphids, to control pests. It leaves no chemical residues on food, usually targets only the pest and can keep working for a long time. However, it is slower than pesticides, may not remove the pest completely, and the control organism could become a pest itself.

Why do farmers use fertilisers?

Triple only Farmers use fertilisers to add mineral ions, such as nitrates, to the soil. Plants need these ions to grow well, so crop yields increase and more food is produced from the same land. However, fertilisers cost money and can be washed off fields into rivers and lakes, polluting water and harming wildlife.

What are the ethical issues with genetic engineering?

The ethical issues with genetic engineering are about what people think is right or wrong. Some people think it is wrong or unnatural to change the genes of living things, especially animals, and there are concerns about animal welfare. Alongside these, there are risks such as unknown effects on the environment and human health.

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