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ADH, FSH and LH

Structure and functions in living organisms · Hormones and temperature control · note 3 of 4

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ADH, FSH and LHSpec 2.95B

In short

ADH, FSH and LH are three hormones released by the pituitary gland at the base of the brain. ADH makes the collecting ducts of the kidney more permeable to water, so more water is reabsorbed. FSH causes an egg to mature in an ovary and stimulates the ovaries to produce oestrogen. LH stimulates ovulation, the release of the egg.

Three more hormones are released by the pituitary gland, at the base of the brain.

ADH, FSH and LH
HormoneSourceRole and effects
ADHPituitary glandControls the water content of the blood. It makes the collecting ducts of the kidney more permeable to water, so more water is reabsorbed into the blood and less urine is made
FSHPituitary glandCauses an egg to mature in an ovary. Stimulates the ovaries to produce oestrogen
LHPituitary glandStimulates the release of the egg (ovulation) from the ovary
ADH and the water content of the blood
Blood water content too lowBlood water content too high
ADH releasedMoreLess
Collecting ductMore permeable to waterLess permeable to water
Water reabsorbed into bloodMoreLess
UrineSmall volume, concentratedLarge volume, dilute
Four stacked graphs over a 28-day cycle: FSH rises early in the cycle and peaks just before day 14, LH has a sharp peak just before ovulation at day 14, oestrogen rises to a peak before ovulation, and progesterone rises after ovulation, peaks around day 21 and falls before menstruation. (opens full size in a new tab)
Levels of FSH, LH, oestrogen and progesterone. The LH surge triggers ovulation around day 14.
Common mistake:

FSH is not the hormone that releases the egg. FSH makes the egg mature; LH stimulates its release.

Written and checked against the Edexcel IGCSE Biology (4BI1) specification · Updated October 2026

Frequently asked questions

Why are hormones called chemical messengers?

Hormones are called chemical messengers because they are chemicals secreted by glands directly into the blood, which carries them to target organs where they cause an effect. Hormonal communication is slower than nervous communication, which uses electrical impulses, but its effects last longer. Hormones reach every part of the body but only affect their target organs.

What does insulin do to blood sugar?

Insulin lowers blood glucose concentration. When blood glucose is high, the pancreas secretes insulin into the blood. Insulin makes cells take up glucose from the blood and makes the liver convert glucose into glycogen for storage, so the blood glucose concentration falls. The pancreas makes insulin, but the liver stores the glycogen.

What does adrenaline do to the body?

Adrenaline prepares the body for fight or flight. It is released by the adrenal glands when a person is frightened or excited. It increases heart rate, so more blood carrying oxygen and glucose reaches the muscles for respiration. It also stimulates the liver to change glycogen into glucose, raising blood glucose.

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