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Absorption in the small intestine

Structure and functions in living organisms · Human nutrition · note 6 of 7

Absorption in the small intestineSpec 2.32

In short

The products of digestion are absorbed in the small intestine, mostly in the ileum. Its wall is covered in villi and microvilli, giving a very large surface area. Each villus has a wall one cell thick for a short diffusion distance, a capillary network that keeps a steep concentration gradient, and a lacteal that absorbs fatty acids and glycerol.

The products of digestion are absorbed in the small intestine, mostly in the ileum. The small intestine is adapted to absorb efficiently. It is long and its inner wall is folded. The wall is covered in millions of tiny finger-like projections called villi (one is a villus).

Adaptations of a villus for absorption
AdaptationHow it helps absorption
Villi and microvilli (tiny projections on each surface cell)Give a very large surface area
Wall (epithelium) is one cell thickShort diffusion distance, so absorption is fast
Network of blood capillaries close to the surfaceCarries glucose and amino acids away. This keeps a steep concentration gradient.
A lacteal (a lymph vessel) in the centreAbsorbs fatty acids and glycerol
A villus in section labelled microvilli, epithelium one cell thick, blood capillaries and lacteal, with glucose and amino acids absorbed into the capillaries and fatty acids and glycerol into the lacteal; beside it a section of ileum wall with folds covered in villi. (opens full size in a new tab)
A villus: microvilli and a one-cell-thick epithelium give a large surface area and short diffusion distance; capillaries and the lacteal carry absorbed food away.

Glucose and amino acids move into the blood capillaries by diffusion and active transport. The blood carries them to the liver and then around the body. Fatty acids and glycerol move into the lacteal.

Exam tip:

For an 'explain how it is adapted' question, give the feature and the reason: 'one cell thick, so there is a short diffusion distance'. Do not say the villi 'absorb more': say they 'increase the surface area'.

Written and checked against the Edexcel IGCSE Biology (4BI1) specification · Updated October 2026

Frequently asked questions

What enzymes digest carbohydrates?

Amylase and maltase digest carbohydrates. Amylase, made in the salivary glands and the pancreas, breaks starch down into the sugar maltose. Maltase, made in the small intestine, then breaks maltose down into glucose. Glucose is small and soluble, so it can be absorbed into the blood in the small intestine and used in respiration.

What enzymes break down proteins?

Proteases break down proteins into amino acids. Proteases are made in the stomach, the pancreas and the small intestine. Pepsin is a protease in the acidic stomach and works best at about pH 2. The amino acids are absorbed into the blood and used to make new proteins for growth and repair.

What enzymes does the pancreas produce?

The pancreas produces amylase, protease and lipase and releases them into the duodenum. Amylase breaks starch into maltose, protease breaks proteins into amino acids, and lipase breaks lipids into fatty acids and glycerol. The pancreas is not part of the alimentary canal itself, but it helps with digestion.

All 5 questions on Human nutrition