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GM crops: advantages and disadvantages

Biotechnology and genetic modification · Genetic modification · note 3 of 3

Spec 21.3.4
Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean
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GM crops: advantages and disadvantagesSpec 21.3.4

In short

GM crops are crop plants such as soya, maize and rice that have been genetically modified, for example herbicide-resistant soya, insect-resistant maize and golden rice. Advantages include higher yields, less insecticide and better nutrition. Disadvantages include genes spreading to wild plants, harm to other organisms, expensive seed and pests becoming resistant to the toxin.

Crops such as soya, maize and rice have been genetically modified. Examples are herbicide-resistant soya, insect-resistant maize (which makes a toxin that kills insect pests that eat it), and golden rice, which makes a substance the body converts to vitamin A.

Advantages and disadvantages of genetically modifying crops
AdvantagesDisadvantages
Higher yield, as less is lost to weeds and insect pestsGene may spread to wild plants (for example weeds could become herbicide resistant)
Less insecticide needed, which saves money and reduces harm to other insectsMay harm other organisms, such as non-pest insects, and reduce biodiversity
Improved nutrition, such as golden rice, which could help to reduce vitamin A deficiencySeeds can be expensive, and farmers may need to buy new seed each year
Crops can be grown in conditions that would otherwise be unsuitable, helping to feed a growing populationSome people are concerned about eating GM food, as long-term effects on health are not fully known
Less time and money spent on spraying insecticideInsect pests may become resistant to the toxin made by the crop
Exam tip:

For 'discuss', give at least one advantage and one disadvantage, and name a crop with its modification, for example insect-resistant maize.

Quick check

  1. Define genetic modification.

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    Changing the genetic material of an organism by removing, changing or inserting individual genes.

  2. Give an example of a human protein made by genetically modified bacteria.

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    Insulin.

  3. Supplement Which enzyme cuts DNA to leave sticky ends?

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    A restriction enzyme.

  4. Supplement Which enzyme joins the gene into the plasmid?

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    DNA ligase.

  5. Supplement Name one disadvantage of GM crops.

    Show answer

    The gene may spread to wild plants; or it may harm other organisms.

Written and checked against the Cambridge IGCSE Biology (0610) specification · Updated October 2026

Frequently asked questions

What is genetic engineering in agriculture?

Genetic engineering in agriculture means genetically modifying crop plants by inserting genes, often from another species. Examples are herbicide-resistant crops, which can be sprayed to kill weeds without being harmed, insect-resistant crops that need less insecticide, and crops with improved nutritional quality, such as golden rice, which contains a vitamin A precursor.

How is human insulin made by bacteria?

Supplement Human insulin is made by inserting the human insulin gene into bacteria. Restriction enzymes cut the gene out of human DNA, leaving sticky ends, and cut open a plasmid with matching sticky ends. DNA ligase joins the gene into the plasmid, making a recombinant plasmid. The bacteria multiply and express the gene, making insulin.

What do restriction enzymes and DNA ligase do?

Supplement Restriction enzymes cut DNA, leaving short single-stranded overhangs called sticky ends, while DNA ligase joins DNA. In genetic modification, the same restriction enzyme cuts out the human gene and cuts open the plasmid, so the sticky ends match. DNA ligase then joins the gene into the plasmid to form a recombinant plasmid.

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