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Physical activity and breathing

Gas exchange in humans · Gas exchange in humans · note 5 of 6

Physical activity and breathingSpec 11.1.5, 11.1.10

In short

During physical activity, both the rate of breathing, the number of breaths per minute, and the depth of breathing, the volume of each breath, increase. This brings more oxygen into the body and removes more carbon dioxide. Muscles respire faster and produce more carbon dioxide, and the brain detects the higher concentration in the blood.

During physical activity, your rate of breathing (the number of breaths per minute) increases. Your depth of breathing (the volume of air in each breath) also increases. Together, these bring more oxygen into the body and remove more carbon dioxide.

Investigating the effect of exercise on breathing

  1. Sit still and count the number of breaths taken in one minute (or count for 30 seconds and double it). This is the resting breathing rate. Repeat and calculate a mean.
  2. Do a set amount of exercise, such as running on the spot for 2 minutes.
  3. Immediately count the breaths in one minute.
  4. Record the rate every minute until it returns to the resting value. To measure depth, use a spirometer to find the volume of each breath, or measure chest expansion with a tape measure around the chest.
  5. Repeat with different intensities of exercise, allowing full recovery between each.
Example results (for practice)
ActivityBreathing rate / breaths per minute
At rest16
After walking22
After running34
Practical skill:

The independent variable is the type or amount of exercise. The dependent variable is the breathing rate. Control the time for each exercise and the time of counting, use the same person, and repeat to find a mean.

Percentage change in breathing rate

A student breathes 16 times per minute at rest and 34 times per minute after running. Calculate the percentage increase.

  1. Increase = 34 − 16 = 18 breaths per minute
  2. Percentage increase = 18 ÷ 16 × 100

Answer: 112.5% (about 113%)

Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean

Why breathing changes during exercise

Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean
  1. Muscles respire faster during exercise, so more carbon dioxide is produced.
  2. The concentration of carbon dioxide in the blood increases.
  3. This increase is detected by the brain.
  4. The brain sends signals to the muscles used in breathing, so the rate of breathing increases and the breaths are deeper.
  5. More carbon dioxide is removed and more oxygen is taken in.
Supplement (what this means)Supplement: only for the Extended papers (2 and 4). Core students can skip it. What the labels mean
Common mistake:

Do not say that the brain detects a lack of oxygen. For this syllabus, the stimulus is the increased concentration of carbon dioxide in the blood.

Written and checked against the Cambridge IGCSE Biology (0610) specification · Updated October 2026

Frequently asked questions

How are alveoli adapted for gas exchange?

Alveoli are adapted for gas exchange by having a large surface area, from millions of alveoli, and thin walls one cell thick, giving a short diffusion distance. A network of capillaries around each alveolus gives a good blood supply, and ventilation brings fresh air. Both keep a steep concentration gradient, so diffusion is fast.

How does the diaphragm help you breathe in?

Supplement When you breathe in, the diaphragm muscles contract, so the diaphragm moves down and flattens. At the same time the external intercostal muscles contract and lift the ribs up and out. The volume of the thorax increases and the pressure falls below the air pressure outside, so air moves into the lungs.

Why does expired air contain more carbon dioxide than inspired air?

Supplement Expired air contains more carbon dioxide because body cells produce carbon dioxide in respiration. It is carried to the lungs in the blood and diffuses into the alveoli, so expired air has about 4% carbon dioxide compared with about 0.04% in inspired air. Expired air also contains less oxygen and more water vapour.

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